{"title":"Home page","description":null,"products":[{"product_id":"essential-vitamins-test","title":"Home Vitamin Deficiency Test UK - B12, Folate \u0026 Vitamin D","description":"\u003cbody\u003e\n\n\n\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cmeta content=\"width=device-width, initial-scale=1\" name=\"viewport\"\u003e\n\u003ctitle\u003eHome Vitamin Deficiency Test UK | B12, Folate \u0026amp; Vitamin D\u003c\/title\u003e\n\u003cmeta content=\"Order a home vitamin deficiency test in the UK. 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hydroxyvitamin D.\"\n    },\n    {\n      \"@type\": \"Product\",\n      \"@id\": \"#product\",\n      \"name\": \"Home Vitamin Deficiency Test UK | B12, Folate \u0026 Vitamin D\",\n      \"alternateName\": [\n        \"Essential Vitamins Test\",\n        \"Home Vitamin Blood Test\",\n        \"Vitamin B12 Folate and Vitamin D Test\",\n        \"Vitamin Deficiency Home Test\"\n      ],\n      \"description\": \"An at home capillary blood test measuring total vitamin B12, serum folate and 25 hydroxyvitamin D.\",\n      \"sku\": \"C1BLP02200\",\n      \"category\": \"Home Vitamin Deficiency Test\",\n      \"brand\": {\n        \"@id\": \"#organization\"\n      },\n      \"isRelatedTo\": {\n        \"@id\": \"#medical-test\"\n      },\n      \"about\": {\n        \"@id\": \"#vitamin-deficiency-test\"\n      },\n      \"additionalProperty\": [\n        {\n          \"@type\": \"PropertyValue\",\n          \"name\": \"Product type\",\n          \"value\": \"At home blood test\"\n        },\n        {\n          \"@type\": \"PropertyValue\",\n          \"name\": \"Specimen type\",\n          \"value\": \"Capillary blood collected into a microtainer\"\n        },\n        {\n          \"@type\": \"PropertyValue\",\n          \"name\": \"Biomarker count\",\n          \"value\": \"3\"\n        },\n        {\n          \"@type\": \"PropertyValue\",\n          \"name\": \"Biomarkers\",\n          \"value\": \"Total vitamin B12, serum folate and 25 hydroxyvitamin D\"\n        },\n        {\n          \"@type\": \"PropertyValue\",\n          \"name\": \"Fasting requirement\",\n          \"value\": \"Fasting is not generally required\"\n        },\n        {\n          \"@type\": \"PropertyValue\",\n          \"name\": \"Laboratory accreditation\",\n          \"value\": \"Processed through UKAS accredited laboratories\"\n        },\n        {\n          \"@type\": \"PropertyValue\",\n          \"name\": \"Regulatory registration\",\n          \"value\": \"Diagnostic pathway uses CQC registered services\"\n        },\n        {\n          \"@type\": \"PropertyValue\",\n          \"name\": \"Collection equipment compliance\",\n          \"value\": \"UKCA and CE marked collection equipment within an ISO 13485 quality management framework\"\n        }\n      ]\n    },\n    {\n      \"@type\": \"MedicalWebPage\",\n      \"@id\": \"#webpage\",\n      \"name\": \"Home Vitamin Deficiency Test UK | B12, Folate \u0026 Vitamin D\",\n      \"description\": \"Order a home vitamin deficiency test in the UK. UKAS accredited and CQC registered labs measure total vitamin B12, serum folate and vitamin D.\",\n      \"inLanguage\": \"en-GB\",\n      \"datePublished\": \"2026-07-26\",\n      \"dateModified\": \"2026-07-26\",\n      \"lastReviewed\": \"2026-07-26\",\n      \"mainEntity\": {\n        \"@id\": \"#product\"\n      },\n      \"about\": [\n        {\n          \"@id\": \"#medical-test\"\n        },\n        {\n          \"@id\": \"#vitamin-deficiency-test\"\n        }\n      ],\n      \"author\": {\n        \"@id\": \"#organization\"\n      },\n      \"publisher\": {\n        \"@id\": \"#organization\"\n      },\n      \"editor\": {\n        \"@id\": \"#dr-rimas-geiga\"\n      },\n      \"accountablePerson\": {\n        \"@id\": \"#dr-laura-geige\"\n      },\n      \"reviewedBy\": [\n        {\n          \"@id\": \"#dr-rimas-geiga\"\n        },\n        {\n          \"@id\": \"#dr-snieguole-geige\"\n        },\n        {\n          \"@id\": \"#dr-laura-geige\"\n        }\n      ],\n      \"contributor\": [\n        {\n          \"@id\": \"#dr-rimas-geiga\"\n        },\n        {\n          \"@id\": \"#dr-snieguole-geige\"\n        },\n        {\n          \"@id\": \"#dr-laura-geige\"\n        }\n      ],\n      \"medicalAudience\": {\n        \"@type\": \"MedicalAudience\",\n        \"audienceType\": \"Patient\"\n      },\n      \"citation\": [\n        \"https:\/\/www.nice.org.uk\/guidance\/ng239\/chapter\/recommendations\",\n        \"https:\/\/www.nhs.uk\/conditions\/vitamin-b12-or-folate-deficiency-anaemia\/diagnosis\/\",\n        \"https:\/\/www.nhs.uk\/conditions\/vitamin-b12-or-folate-deficiency-anaemia\/treatment\/\",\n        \"https:\/\/www.gloshospitals.nhs.uk\/our-services\/services-we-offer\/pathology\/tests-and-investigations\/vitamin-b12-and-serum-folate\/\",\n        \"https:\/\/cks.nice.org.uk\/topics\/vitamin-d-deficiency-in-adults\/\",\n        \"https:\/\/swlimo.southwestlondon.icb.nhs.uk\/wp-content\/uploads\/SWL-Vitamin-D-Guidelines-for-Adults-and-Children.pdf\",\n        \"https:\/\/www.nice.org.uk\/guidance\/ng247\/chapter\/Recommendations\",\n        \"https:\/\/www.ukas.com\/accreditation\/standards\/medical-laboratory-accreditation\/\",\n        \"https:\/\/www.cqc.org.uk\/guidance-regulation\/providers\/registration\/scope-registration\/regulated-activities\/diagnostic-and-screening-procedures\"\n      ]\n    },\n    {\n      \"@type\": \"FAQPage\",\n      \"@id\": \"#faq\",\n      \"mainEntity\": [\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can I test vitamin levels at home?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Yes. This kit uses capillary blood collected at home and returned for laboratory analysis. It measures total vitamin B12, serum folate and 25 hydroxyvitamin D.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What vitamins does this blood test check?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"The panel checks total vitamin B12, serum folate, also known as vitamin B9, and 25 hydroxyvitamin D.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is this a complete vitamin and mineral blood test?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"No. It measures three vitamins only. It does not include iron, ferritin, magnesium, zinc, calcium, vitamin B6, vitamin C or other micronutrients.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Do I need to fast for a vitamin blood test?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Fasting is not generally required for these three markers. Follow the kit instructions and record supplements, injections and recent high dose treatment.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Should I stop vitamin supplements before the test?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Do not stop prescribed supplements or injections without clinical advice. Supplements can influence results, so record the product, dose and timing. Where deficiency is being investigated, samples are ideally taken before replacement begins.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What is the difference between total B12 and active B12?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Total B12 measures vitamin B12 bound to several carrier proteins. Active B12 measures holotranscobalamin, the fraction available to cells. This product reports total B12 only.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can a normal vitamin B12 result rule out deficiency?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"No. Symptoms, supplements, pregnancy, medicines and laboratory limitations matter. Borderline or discordant results may require active B12, methylmalonic acid, homocysteine, a full blood count or further investigation.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What symptoms can occur with vitamin B12 deficiency?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Possible symptoms include tiredness, breathlessness, a sore tongue, pins and needles, numbness, balance problems, memory or concentration changes and visual symptoms. Neurological symptoms can occur without anaemia.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What can cause low vitamin B12?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Possible causes include autoimmune gastritis, pernicious anaemia, coeliac disease, bowel surgery, medicines such as metformin or proton pump inhibitors, dietary insufficiency and other malabsorption conditions.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What does a high vitamin B12 result mean?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"A high result is commonly caused by supplements or injections. Persistent unexplained elevation can also occur with liver, kidney, inflammatory or blood conditions and may require clinical review.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is a high vitamin B12 result toxic?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"A high blood concentration does not usually mean acute vitamin B12 toxicity. It may reflect supplementation or another health condition, so interpretation should focus on the cause rather than assuming the vitamin itself is causing symptoms.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What does serum folate measure?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Serum folate reflects folate circulating in the blood and can change with recent dietary intake or supplements. It is useful in context but does not independently establish the cause of deficiency.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What can cause low folate?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Possible causes include low dietary intake, alcohol, coeliac disease, malabsorption, pregnancy, increased cell turnover and medicines such as methotrexate, some antiepileptics and trimethoprim.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What does a high folate result mean?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"A high serum folate result most often reflects recent food fortification or folic acid supplementation. It is not usually a toxicity diagnosis, but supplement use and vitamin B12 status should be reviewed.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can folic acid mask vitamin B12 deficiency?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Yes. Folic acid can improve the anaemia caused by vitamin B12 deficiency while neurological injury continues. Vitamin B12 should be assessed before treating suspected folate deficiency.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"How much folic acid is recommended before pregnancy?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"UK guidance advises most people who may become pregnant to take 400 micrograms daily before conception and through the first 12 weeks of pregnancy. Higher dose folic acid is used only for defined higher risk situations under clinical advice.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What vitamin D level is considered deficient in the UK?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Many UK pathways classify a 25 hydroxyvitamin D result below 25 nmol\/L as deficient.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What vitamin D level is considered insufficient?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"A level from 25 to 50 nmol\/L may be inadequate for some people. Symptoms, bone health, risk factors, supplements and local laboratory guidance affect management.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What vitamin D level is considered sufficient?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"A result above 50 nmol\/L is considered sufficient for most adults in many UK pathways. Higher is not automatically better.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can vitamin D levels be too high?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Yes. Very high vitamin D is most commonly caused by excessive supplementation and may lead to high calcium, causing thirst, frequent urination, nausea, constipation, weakness or confusion.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can low vitamin D cause tiredness or low mood?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Low vitamin D may coexist with tiredness, muscle weakness or bone pain, but these symptoms are non specific. A result should not be used to attribute all tiredness or mood symptoms to vitamin D.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"What tests may be needed after a low B12 or folate result?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"A clinician may request a full blood count, blood film, active B12, methylmalonic acid, homocysteine, intrinsic factor antibodies, coeliac testing or other investigations based on symptoms and history.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"When are vitamin deficiency symptoms urgent?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Seek prompt medical assessment for new weakness, difficulty walking, rapidly worsening numbness, confusion, visual change, seizures, severe breathlessness, chest pain or symptoms during pregnancy.\"\n          }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Are the laboratories UKAS accredited and CQC registered?\",\n          \"acceptedAnswer\": {\n            \"@type\": \"Answer\",\n            \"text\": \"Samples are processed through UKAS accredited laboratories within a CQC registered diagnostic pathway. Collection equipment is UKCA and CE marked and supported by an ISO 13485 quality management framework.\"\n          }\n        }\n      ]\n    },\n    {\n      \"@type\": \"HowTo\",\n      \"@id\": \"#howto\",\n      \"name\": \"How to complete the home vitamin deficiency test\",\n      \"description\": \"Record supplements and medicines, collect capillary blood at home and return it for accredited laboratory analysis.\",\n      \"step\": [\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 1,\n          \"name\": \"Record supplements and medicines\",\n          \"text\": \"Record vitamin B12, folic acid, vitamin D, injections, fortified products and relevant medicines.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 2,\n          \"name\": \"Collect the sample\",\n          \"text\": \"Collect capillary blood into the supplied microtainer.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 3,\n          \"name\": \"Return the sample\",\n          \"text\": \"Package and return the sample using the supplied transport materials.\"\n        },\n        {\n          \"@type\": \"HowToStep\",\n          \"position\": 4,\n          \"name\": \"Review the cause and wider context\",\n          \"text\": \"Interpret vitamin concentrations with symptoms, diet, supplements, medicines, absorption and related blood tests.\"\n        }\n      ]\n    },\n    {\n      \"@type\": \"Review\",\n      \"@id\": \"#clinical-content-review\",\n      \"name\": \"Vitamin profile nutritional evidence, safety and governance review\",\n      \"reviewBody\": \"The page was reviewed for total vitamin B12, serum folate and vitamin D interpretation, supplement effects, pregnancy guidance, neurological symptoms and further testing limitations.\",\n      \"datePublished\": \"2026-07-26\",\n      \"author\": {\n        \"@id\": \"#dr-rimas-geiga\"\n      },\n      \"contributor\": [\n        {\n          \"@id\": \"#dr-snieguole-geige\"\n        },\n        {\n          \"@id\": \"#dr-laura-geige\"\n        }\n      ],\n      \"itemReviewed\": {\n        \"@id\": \"#webpage\"\n      }\n    }\n  ]\n}\u003c\/script\u003e\n\n\u003carticle class=\"vitamin_product\"\u003e\n\u003csection class=\"vitamin_hero\"\u003e\n\u003cp class=\"vitamin_eyebrow\"\u003eAt home vitamin blood test\u003c\/p\u003e\n\u003ch2\u003eHome Vitamin Deficiency Test UK | B12, Folate \u0026amp; Vitamin D\u003c\/h2\u003e\n\u003cp class=\"vitamin_lead\"\u003e\u003cstrong\u003eA three marker home blood test measuring total vitamin B12, serum folate and vitamin D through a UK laboratory pathway.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe panel provides selected information about vitamins involved in blood formation, neurological health, DNA synthesis and bone health. Results should be interpreted with symptoms, supplements, medicines, diet and possible absorption problems.\u003c\/p\u003e\n\u003cdiv class=\"vitamin_grid\"\u003e\n\u003cdiv class=\"vitamin_stat\"\u003e\n\u003cstrong\u003e3 biomarkers\u003c\/strong\u003e\u003cspan\u003eTotal vitamin B12, serum folate and 25 hydroxyvitamin D\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_stat\"\u003e\n\u003cstrong\u003eHome collection\u003c\/strong\u003e\u003cspan\u003eCapillary blood collected into the supplied microtainer\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_stat\"\u003e\n\u003cstrong\u003eUK laboratory pathway\u003c\/strong\u003e\u003cspan\u003eUKAS accredited and CQC registered laboratory processing\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_stat\"\u003e\n\u003cstrong\u003eProduct code\u003c\/strong\u003e\u003cspan\u003eC1BLP02200\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_notice\"\u003e\n\u003cstrong\u003eFocused vitamin profile, not a complete nutritional screen\u003c\/strong\u003e\n\u003cp\u003eThis product does not include a full blood count, ferritin, iron, calcium, magnesium, zinc, active B12, methylmalonic acid, homocysteine or tests for the cause of malabsorption.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_warning\"\u003e\n\u003cstrong\u003eNeurological or severe symptoms should not wait for home testing\u003c\/strong\u003e\n\u003cp\u003eSeek prompt medical assessment for new weakness, difficulty walking, rapidly worsening numbness, confusion, visual change, seizures, severe breathlessness, chest pain or concerning symptoms during pregnancy.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section\"\u003e\n\u003cp class=\"vitamin_eyebrow\"\u003eQuality and compliance\u003c\/p\u003e\n\u003ch3\u003eHome vitamin testing supported by UK standards\u003c\/h3\u003e\n\u003cdiv class=\"vitamin_trust_grid\"\u003e\n\u003cdiv class=\"vitamin_trust_item\"\u003e\n\u003cstrong\u003eUKAS accredited laboratories\u003c\/strong\u003e\n\u003cspan\u003eISO 15189 accreditation supports laboratory competence, quality systems and diagnostic performance.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_trust_item\"\u003e\n\u003cstrong\u003eCQC registered services\u003c\/strong\u003e\n\u003cspan\u003eThe diagnostic pathway uses organisations registered with the Care Quality Commission.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_trust_item\"\u003e\n\u003cstrong\u003eCompliant collection equipment\u003c\/strong\u003e\n\u003cspan\u003eUKCA and CE marked equipment supported by an ISO 13485 quality management framework.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_trust_item\"\u003e\n\u003cstrong\u003eClinically bounded claims\u003c\/strong\u003e\n\u003cspan\u003eThe page distinguishes a vitamin concentration from diagnosis, symptom attribution and treatment decisions.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section\"\u003e\n\u003ch3\u003eWhat this vitamin deficiency test measures\u003c\/h3\u003e\n\u003cdiv class=\"vitamin_table_wrap\"\u003e\n\u003ctable class=\"vitamin_table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth scope=\"col\"\u003eMarker\u003c\/th\u003e\n\u003cth scope=\"col\"\u003ePrimary role\u003c\/th\u003e\n\u003cth scope=\"col\"\u003eImportant limitation\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTotal vitamin B12\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRed blood cell production, DNA synthesis and neurological function\u003c\/td\u003e\n\u003ctd\u003eTotal B12 is not the same as active B12 and may need confirmatory testing.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSerum folate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eDNA synthesis, cell division and red blood cell production\u003c\/td\u003e\n\u003ctd\u003eReflects recent intake and must be interpreted with vitamin B12.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e25 hydroxyvitamin D\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCalcium regulation, bones and muscle function\u003c\/td\u003e\n\u003ctd\u003eSymptoms are non specific and higher levels are not automatically better.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section\"\u003e\n\u003ch3\u003eWho may consider this test?\u003c\/h3\u003e\n\u003cp\u003eThis home vitamin blood test may be considered by adults seeking selected vitamin information in the context of:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePersistent tiredness, weakness or a sore tongue alongside clinical assessment\u003c\/li\u003e\n\u003cli\u003ePins and needles, numbness, balance or memory concerns\u003c\/li\u003e\n\u003cli\u003eBone pain, muscle weakness or known osteoporosis risk\u003c\/li\u003e\n\u003cli\u003eA vegan or highly restricted diet\u003c\/li\u003e\n\u003cli\u003eCoeliac disease, bowel surgery, inflammatory bowel disease or another malabsorption risk\u003c\/li\u003e\n\u003cli\u003eMetformin, proton pump inhibitors, antiepileptics or other relevant medicines\u003c\/li\u003e\n\u003cli\u003ePregnancy planning or pregnancy where folate advice is required\u003c\/li\u003e\n\u003cli\u003eA previous low, high or borderline vitamin result\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTiredness and low mood are non specific and may have causes not measured by this panel.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section\"\u003e\n\u003ch3\u003eHow the home vitamin test works\u003c\/h3\u003e\n\u003cdiv class=\"vitamin_steps\"\u003e\n\u003cdiv class=\"vitamin_step\"\u003e\n\u003cspan class=\"vitamin_step_number\"\u003e1\u003c\/span\u003e\n\u003ch4\u003eRecord supplements and medicines\u003c\/h4\u003e\n\u003cp\u003eNote all tablets, sprays, injections, fortified products, medicines and recent treatment.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_step\"\u003e\n\u003cspan class=\"vitamin_step_number\"\u003e2\u003c\/span\u003e\n\u003ch4\u003eCollect and return\u003c\/h4\u003e\n\u003cp\u003eCollect capillary blood into the supplied microtainer and return it using the provided packaging.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_step\"\u003e\n\u003cspan class=\"vitamin_step_number\"\u003e3\u003c\/span\u003e\n\u003ch4\u003eReview the cause, not only the number\u003c\/h4\u003e\n\u003cp\u003eInterpret each result with symptoms, diet, absorption, medicines and related blood tests.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section\"\u003e\n\u003ch3\u003ePreparing for the test\u003c\/h3\u003e\n\u003cdiv class=\"vitamin_table_wrap\"\u003e\n\u003ctable class=\"vitamin_table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth scope=\"col\"\u003ePreparation\u003c\/th\u003e\n\u003cth scope=\"col\"\u003eWhat to do\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFasting\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eFasting is not generally required. Follow the supplied kit instructions.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVitamin B12\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRecord tablets, oral sprays, injections and the date of the most recent dose.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFolate\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRecord folic acid, prenatal vitamins, fortified products and relevant medicines.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVitamin D\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRecord the daily or weekly dose, calcium products and any recent loading course.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePrescribed treatment\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eDo not stop prescribed replacement or injections unless a clinician advises you to do so.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePregnancy\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRecord pregnancy or pregnancy planning and follow NHS folic acid and vitamin D advice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRelated conditions\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRecord coeliac disease, bowel surgery, autoimmune gastritis, kidney disease, liver disease and malabsorption.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section\"\u003e\n\u003ch3\u003eCommon vitamin result patterns\u003c\/h3\u003e\n\u003cp\u003eThese simplified patterns support discussion and are not diagnoses.\u003c\/p\u003e\n\u003cdiv class=\"vitamin_table_wrap\"\u003e\n\u003ctable class=\"vitamin_table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth scope=\"col\"\u003ePattern\u003c\/th\u003e\n\u003cth scope=\"col\"\u003ePossible context\u003c\/th\u003e\n\u003cth scope=\"col\"\u003ePossible next step\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLow B12 with neurological symptoms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMay indicate clinically important deficiency even without confirmed anaemia.\u003c\/td\u003e\n\u003ctd\u003eArrange prompt medical assessment and investigation of the cause.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBorderline B12 with persistent symptoms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eTotal B12 may not fully reflect functional deficiency.\u003c\/td\u003e\n\u003ctd\u003eConsider active B12, methylmalonic acid, homocysteine and a full blood count.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLow folate with unknown B12 status\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eFolate replacement could improve anaemia while untreated B12 neurological injury continues.\u003c\/td\u003e\n\u003ctd\u003eAssess vitamin B12 before starting folic acid treatment.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eHigh B12 or folate while supplementing\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eOften reflects recent tablets, injections or fortified products.\u003c\/td\u003e\n\u003ctd\u003eReview dose and timing rather than assuming toxicity.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVitamin D below 25 nmol\/L\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eDeficiency associated with musculoskeletal and bone health risk.\u003c\/td\u003e\n\u003ctd\u003eDiscuss replacement and whether calcium or other investigations are required.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section\"\u003e\n\u003ch3\u003eBiomarkers and result interpretation\u003c\/h3\u003e\n\u003cp\u003eSelect each marker to read what it measures, preparation guidance and how low, normal, high or urgent results may be considered.\u003c\/p\u003e\n\u003cdetails class=\"vitamin_biomarker\"\u003e\n\u003csummary\u003eTotal vitamin B12\u003c\/summary\u003e\n\u003cdiv class=\"vitamin_biomarker_body\"\u003e\n\u003cp\u003eVitamin B12 supports red blood cell formation, DNA synthesis and normal neurological function. This test measures total circulating vitamin B12 rather than active B12.\u003c\/p\u003e\n\u003cp\u003eTotal B12 is useful as a first line marker but should be interpreted with symptoms, a full blood count, supplement use, medicines and possible malabsorption. Neurological deficiency can occur without anaemia.\u003c\/p\u003e\n\u003cdiv class=\"vitamin_subnote\"\u003e\n\u003cstrong\u003eBorderline results\u003c\/strong\u003e\n\u003cp\u003eWhere symptoms and total B12 do not agree, NICE guidance may support further testing with active B12, methylmalonic acid or homocysteine depending on the clinical situation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_subnote\"\u003e\n\u003cstrong\u003eBefore testing\u003c\/strong\u003e\n\u003cp\u003eFasting is not generally required. Record multivitamins, vitamin B12 tablets, sprays or injections, folic acid, vitamin D, calcium products and any recent high dose treatment. Do not stop prescribed supplements without medical advice.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch4\u003eHow to understand this result\u003c\/h4\u003e\n\u003cdiv class=\"vitamin_table_wrap\"\u003e\n\u003ctable class=\"vitamin_table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth scope=\"col\"\u003eResult\u003c\/th\u003e\n\u003cth scope=\"col\"\u003eWhat it may mean\u003c\/th\u003e\n\u003cth scope=\"col\"\u003eWhat to do\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_critical\"\u003eCritical low\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eA markedly low result may support significant deficiency, particularly with neurological or haematological symptoms.\u003c\/td\u003e\n\u003ctd\u003eArrange prompt clinical review. Do not delay treatment where a clinician suspects serious neurological involvement.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_low\"\u003eLow\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eMay occur with autoimmune gastritis, pernicious anaemia, dietary insufficiency, malabsorption, bowel surgery or medicine effects.\u003c\/td\u003e\n\u003ctd\u003eDiscuss the cause, a full blood count and whether confirmatory or treatment tests are needed.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_normal\"\u003eNormal\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eFalls within the laboratory interval.\u003c\/td\u003e\n\u003ctd\u003eA normal result does not completely exclude deficiency when symptoms, supplements or clinical risk remain significant.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_high\"\u003eHigh\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eMost commonly reflects supplements or injections, but persistent unexplained elevation can occur with liver, kidney, inflammatory or haematological conditions.\u003c\/td\u003e\n\u003ctd\u003eReview supplement timing and discuss a persistent unexplained result with a GP.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_critical\"\u003eCritical high\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eA very high result is not usually an acute toxicity diagnosis, but may warrant investigation when not explained by treatment.\u003c\/td\u003e\n\u003ctd\u003eSeek clinical review rather than assuming the vitamin itself is causing severe symptoms.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"vitamin_biomarker\"\u003e\n\u003csummary\u003eVitamin D (25 hydroxyvitamin D)\u003c\/summary\u003e\n\u003cdiv class=\"vitamin_biomarker_body\"\u003e\n\u003cp\u003e25 hydroxyvitamin D is the standard blood marker used to assess vitamin D status. Vitamin D supports calcium regulation, bones and muscle function.\u003c\/p\u003e\n\u003cp\u003eRoutine testing is not recommended for every asymptomatic adult. The result should be considered with musculoskeletal symptoms, bone health, sunlight exposure, skin pigmentation, diet, supplements and medical history.\u003c\/p\u003e\n\u003cdiv class=\"vitamin_subnote\"\u003e\n\u003cstrong\u003eBefore testing\u003c\/strong\u003e\n\u003cp\u003eFasting is not generally required. Record multivitamins, vitamin B12 tablets, sprays or injections, folic acid, vitamin D, calcium products and any recent high dose treatment. Do not stop prescribed supplements without medical advice.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch4\u003eHow to understand this result\u003c\/h4\u003e\n\u003cdiv class=\"vitamin_table_wrap\"\u003e\n\u003ctable class=\"vitamin_table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth scope=\"col\"\u003eResult\u003c\/th\u003e\n\u003cth scope=\"col\"\u003eWhat it may mean\u003c\/th\u003e\n\u003cth scope=\"col\"\u003eWhat to do\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_low\"\u003eDeficient\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eBelow 25 nmol\/L is classified as deficient in many UK pathways.\u003c\/td\u003e\n\u003ctd\u003eDiscuss replacement, possible causes and whether calcium or other investigations are required.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_low\"\u003eInsufficient\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e25 to 50 nmol\/L may be inadequate for some people, particularly where symptoms or risk factors are present.\u003c\/td\u003e\n\u003ctd\u003eReview supplementation, diet and safe sunlight advice with a clinician or pharmacist.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_normal\"\u003eSufficient\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eAbove 50 nmol\/L is sufficient for most adults in many UK pathways.\u003c\/td\u003e\n\u003ctd\u003eAvoid assuming that progressively higher levels provide additional benefit.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_high\"\u003eHigh\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eA high result is commonly related to supplementation and may require review of the dose and calcium status.\u003c\/td\u003e\n\u003ctd\u003eStop non prescribed high dose products and seek clinical advice.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_critical\"\u003eConsider toxicity\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eVery high vitamin D can cause hypercalcaemia, with thirst, frequent urination, nausea, constipation, weakness or confusion.\u003c\/td\u003e\n\u003ctd\u003eArrange prompt medical assessment.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"vitamin_biomarker\"\u003e\n\u003csummary\u003eSerum folate (vitamin B9)\u003c\/summary\u003e\n\u003cdiv class=\"vitamin_biomarker_body\"\u003e\n\u003cp\u003eFolate is needed for DNA synthesis and normal red blood cell production. Serum folate reflects recent circulating folate and can change with diet, fortified food and supplements.\u003c\/p\u003e\n\u003cp\u003eA low result may support deficiency, but the cause must be investigated. Vitamin B12 should be assessed before folic acid treatment because folic acid can improve anaemia while neurological B12 deficiency continues.\u003c\/p\u003e\n\u003cdiv class=\"vitamin_subnote\"\u003e\n\u003cstrong\u003ePregnancy planning\u003c\/strong\u003e\n\u003cp\u003eMost people who may become pregnant are advised to take 400 micrograms of folic acid daily before conception and through the first 12 weeks. Higher doses require clinical guidance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_subnote\"\u003e\n\u003cstrong\u003eBefore testing\u003c\/strong\u003e\n\u003cp\u003eFasting is not generally required. Record multivitamins, vitamin B12 tablets, sprays or injections, folic acid, vitamin D, calcium products and any recent high dose treatment. Do not stop prescribed supplements without medical advice.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch4\u003eHow to understand this result\u003c\/h4\u003e\n\u003cdiv class=\"vitamin_table_wrap\"\u003e\n\u003ctable class=\"vitamin_table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth scope=\"col\"\u003eResult\u003c\/th\u003e\n\u003cth scope=\"col\"\u003eWhat it may mean\u003c\/th\u003e\n\u003cth scope=\"col\"\u003eWhat to do\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_critical\"\u003eCritical low\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eA markedly low result may support significant folate deficiency, particularly with anaemia, pregnancy or severe nutritional risk.\u003c\/td\u003e\n\u003ctd\u003eArrange prompt clinical review and assess vitamin B12 before treatment.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_low\"\u003eLow\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eMay occur with low intake, alcohol, malabsorption, pregnancy, increased requirements or medicines.\u003c\/td\u003e\n\u003ctd\u003eDiscuss diet, medicines, a full blood count, vitamin B12 and the underlying cause.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_normal\"\u003eNormal\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eFalls within the laboratory reference interval.\u003c\/td\u003e\n\u003ctd\u003eA normal serum folate does not rule out every cause of anaemia or neurological symptoms.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_high\"\u003eHigh\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eMost often reflects recent dietary intake, fortified foods or folic acid supplementation.\u003c\/td\u003e\n\u003ctd\u003eReview supplement dose and vitamin B12 status rather than treating the number as toxicity.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan class=\"vitamin_status vitamin_critical\"\u003eCritical high\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eA very high serum result is usually supplement related and is not itself a reliable explanation for severe neurological symptoms.\u003c\/td\u003e\n\u003ctd\u003eDiscuss high dose folic acid use and ensure vitamin B12 deficiency has not been overlooked.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section\"\u003e\n\u003ch3\u003eWhat this panel does not include\u003c\/h3\u003e\n\u003cdiv class=\"vitamin_table_wrap\"\u003e\n\u003ctable class=\"vitamin_table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth scope=\"col\"\u003eNot included\u003c\/th\u003e\n\u003cth scope=\"col\"\u003eWhy it may matter\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFull blood count and blood film\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMay identify anaemia, macrocytosis and other blood cell changes.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eActive B12\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMeasures holotranscobalamin and may help when total B12 is borderline or discordant.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMethylmalonic acid and homocysteine\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMay support assessment of functional vitamin B12 or folate deficiency.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eIntrinsic factor antibodies\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMay support investigation of autoimmune gastritis or pernicious anaemia.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFerritin and iron studies\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eIron deficiency can coexist with B12 or folate deficiency and also cause tiredness or anaemia.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCalcium, phosphate and parathyroid hormone\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMay be required where vitamin D is very low, very high or associated with bone or calcium symptoms.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section\" id=\"content-standards\"\u003e\n\u003cp class=\"vitamin_eyebrow\"\u003eEvidence and content standards\u003c\/p\u003e\n\u003ch3\u003eHow this product information was prepared\u003c\/h3\u003e\n\u003cp\u003eThis page was prepared from the supplied three marker Essential Vitamins specification and checked against current NICE, NHS, UKAS and CQC information on total vitamin B12, serum folate, vitamin D, supplement interference, pregnancy and further investigation.\u003c\/p\u003e\n\u003cdiv class=\"vitamin_method_grid\"\u003e\n\u003cdiv class=\"vitamin_method_item\"\u003e\n\u003cstrong\u003eProduct specification checked\u003c\/strong\u003e\n\u003cspan\u003eAt home format, capillary specimen, three biomarkers, supplement guidance and product code.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_method_item\"\u003e\n\u003cstrong\u003eUK clinical evidence checked\u003c\/strong\u003e\n\u003cspan\u003eNICE and NHS sources used for B12 limitations, folate safety, pregnancy advice and vitamin D categories.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_method_item\"\u003e\n\u003cstrong\u003eErrors corrected\u003c\/strong\u003e\n\u003cspan\u003eUnsupported high B12 and high folate toxicity claims were removed, and the risk of masking B12 deficiency was added.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_method_item\"\u003e\n\u003cstrong\u003eReview cycle\u003c\/strong\u003e\n\u003cspan\u003eReview at least annually and earlier when vitamin guidance, laboratory methods or pregnancy advice changes.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section\" id=\"medical-review\"\u003e\n\u003cp class=\"vitamin_eyebrow\"\u003eClinical accountability\u003c\/p\u003e\n\u003ch3\u003eNutritional evidence, patient safety and clinical governance review\u003c\/h3\u003e\n\u003cp\u003eThe review roles are separated across nutritional interpretation, medical safety and clinical governance. The reviewers are not presented as consultant haematologists or metabolic bone specialists.\u003c\/p\u003e\n\u003cdiv class=\"vitamin_review_grid\"\u003e\n\u003carticle class=\"vitamin_review_card\"\u003e\n\u003cdiv class=\"vitamin_review_card_top\"\u003e\n\u003cdiv aria-label=\"Portrait of Dr Rimas Geiga\" class=\"vitamin_review_avatar vitamin_review_avatar_rimas\" role=\"img\"\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cspan class=\"vitamin_review_label\"\u003eNutritional and healthy ageing evidence reviewed by\u003c\/span\u003e\n\u003ch4 class=\"vitamin_review_name\"\u003eDr Rimas Geiga\u003c\/h4\u003e\n\u003cp class=\"vitamin_review_title\"\u003eMedical Doctor, Nutritional Sciences Adviser and Healthy Ageing Expert\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"vitamin_review_scope\"\u003eReviewed dietary and supplement context, vitamin D, B12 and folate interpretation, malabsorption risks and responsible nutrition information.\u003c\/p\u003e\n\u003ca class=\"vitamin_review_link\" href=\"\/pages\/dr-rimas-geiga-medical-doctor-nutritional-sciences-adviser-and-healthy-ageing-expert\"\u003eView professional profile\u003c\/a\u003e\n\u003c\/article\u003e\n\u003carticle class=\"vitamin_review_card\"\u003e\n\u003cdiv class=\"vitamin_review_card_top\"\u003e\n\u003cdiv aria-label=\"Portrait of Dr Snieguole Geige\" class=\"vitamin_review_avatar vitamin_review_avatar_snieguole\" role=\"img\"\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cspan class=\"vitamin_review_label\"\u003eMedical safety and deficiency limitations reviewed by\u003c\/span\u003e\n\u003ch4 class=\"vitamin_review_name\"\u003eDr Snieguole Geige\u003c\/h4\u003e\n\u003cp class=\"vitamin_review_title\"\u003eDentist, Medical Doctor and Senior Adviser\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"vitamin_review_scope\"\u003eReviewed neurological warning signs, folic acid masking risk, pregnancy cautions, medicine disclosure and appropriate follow up.\u003c\/p\u003e\n\u003ca class=\"vitamin_review_link\" href=\"\/pages\/dr-snieguole-geige-dentist-medical-doctor-and-senior-adviser\"\u003eView professional profile\u003c\/a\u003e\n\u003c\/article\u003e\n\u003carticle class=\"vitamin_review_card\"\u003e\n\u003cdiv class=\"vitamin_review_card_top\"\u003e\n\u003cdiv aria-label=\"Portrait of Dr Laura Geige\" class=\"vitamin_review_avatar vitamin_review_avatar_laura\" role=\"img\"\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cspan class=\"vitamin_review_label\"\u003eClinical governance and patient communication oversight\u003c\/span\u003e\n\u003ch4 class=\"vitamin_review_name\"\u003eDr Laura Geige\u003c\/h4\u003e\n\u003cp class=\"vitamin_review_title\"\u003eMedical Director, Senior Practitioner and Skin Expert\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"vitamin_review_scope\"\u003eReviewed claims compliance, patient facing clarity, supplement boundaries and the distinction between a laboratory concentration and a clinical diagnosis.\u003c\/p\u003e\n\u003ca class=\"vitamin_review_link\" href=\"\/pages\/dr-laura-geige-medical-director-senior-practitioner-and-skin-expert\"\u003eView professional profile\u003c\/a\u003e\n\u003c\/article\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"vitamin_review_meta\"\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eEvidence checked\u003c\/strong\u003e\n\u003cspan\u003e26 July 2026\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eClinical review date\u003c\/strong\u003e\n\u003cspan\u003e26 July 2026\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eNext scheduled review\u003c\/strong\u003e\n\u003cspan\u003eBy 26 July 2027 or earlier when UK guidance changes\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp class=\"vitamin_board_link\"\u003e\u003ca href=\"\/pages\/medical-advisory-board\"\u003eMeet the Grace Belgravia Medical Advisory Board\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section vitamin_sources\"\u003e\n\u003cp class=\"vitamin_eyebrow\"\u003eAuthoritative references\u003c\/p\u003e\n\u003ch3\u003eUK vitamin testing and deficiency sources\u003c\/h3\u003e\n\u003cdetails\u003e\n\u003csummary\u003eView the evidence sources used\u003c\/summary\u003e\n\u003cdiv class=\"vitamin_sources_body\"\u003e\n\u003cul\u003e\n\u003cli\u003eNICE NG239: vitamin B12 deficiency in adults\u003c\/li\u003e\n\u003cli\u003eNHS: vitamin B12 or folate deficiency anaemia diagnosis and treatment\u003c\/li\u003e\n\u003cli\u003eNHS laboratory guidance on total vitamin B12 and serum folate\u003c\/li\u003e\n\u003cli\u003eNICE CKS: vitamin D deficiency in adults\u003c\/li\u003e\n\u003cli\u003eSouth West London NHS vitamin D guidance\u003c\/li\u003e\n\u003cli\u003eNICE maternal and child nutrition guidance on folic acid\u003c\/li\u003e\n\u003cli\u003eUKAS ISO 15189 medical laboratory accreditation information\u003c\/li\u003e\n\u003cli\u003eCQC guidance on diagnostic and screening procedures\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_section vitamin_faq\"\u003e\n\u003cp class=\"vitamin_eyebrow\"\u003eSearch led questions\u003c\/p\u003e\n\u003ch3\u003eHome vitamin deficiency test FAQs\u003c\/h3\u003e\n\u003cdetails\u003e\n\u003csummary\u003eCan I test vitamin levels at home?\u003c\/summary\u003e\n\u003cp\u003eYes. This kit uses capillary blood collected at home and returned for laboratory analysis. It measures total vitamin B12, serum folate and 25 hydroxyvitamin D.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat vitamins does this blood test check?\u003c\/summary\u003e\n\u003cp\u003eThe panel checks total vitamin B12, serum folate, also known as vitamin B9, and 25 hydroxyvitamin D.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eIs this a complete vitamin and mineral blood test?\u003c\/summary\u003e\n\u003cp\u003eNo. It measures three vitamins only. It does not include iron, ferritin, magnesium, zinc, calcium, vitamin B6, vitamin C or other micronutrients.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eDo I need to fast for a vitamin blood test?\u003c\/summary\u003e\n\u003cp\u003eFasting is not generally required for these three markers. Follow the kit instructions and record supplements, injections and recent high dose treatment.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eShould I stop vitamin supplements before the test?\u003c\/summary\u003e\n\u003cp\u003eDo not stop prescribed supplements or injections without clinical advice. Supplements can influence results, so record the product, dose and timing. Where deficiency is being investigated, samples are ideally taken before replacement begins.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat is the difference between total B12 and active B12?\u003c\/summary\u003e\n\u003cp\u003eTotal B12 measures vitamin B12 bound to several carrier proteins. Active B12 measures holotranscobalamin, the fraction available to cells. This product reports total B12 only.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eCan a normal vitamin B12 result rule out deficiency?\u003c\/summary\u003e\n\u003cp\u003eNo. Symptoms, supplements, pregnancy, medicines and laboratory limitations matter. Borderline or discordant results may require active B12, methylmalonic acid, homocysteine, a full blood count or further investigation.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat symptoms can occur with vitamin B12 deficiency?\u003c\/summary\u003e\n\u003cp\u003ePossible symptoms include tiredness, breathlessness, a sore tongue, pins and needles, numbness, balance problems, memory or concentration changes and visual symptoms. Neurological symptoms can occur without anaemia.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat can cause low vitamin B12?\u003c\/summary\u003e\n\u003cp\u003ePossible causes include autoimmune gastritis, pernicious anaemia, coeliac disease, bowel surgery, medicines such as metformin or proton pump inhibitors, dietary insufficiency and other malabsorption conditions.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat does a high vitamin B12 result mean?\u003c\/summary\u003e\n\u003cp\u003eA high result is commonly caused by supplements or injections. Persistent unexplained elevation can also occur with liver, kidney, inflammatory or blood conditions and may require clinical review.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eIs a high vitamin B12 result toxic?\u003c\/summary\u003e\n\u003cp\u003eA high blood concentration does not usually mean acute vitamin B12 toxicity. It may reflect supplementation or another health condition, so interpretation should focus on the cause rather than assuming the vitamin itself is causing symptoms.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat does serum folate measure?\u003c\/summary\u003e\n\u003cp\u003eSerum folate reflects folate circulating in the blood and can change with recent dietary intake or supplements. It is useful in context but does not independently establish the cause of deficiency.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat can cause low folate?\u003c\/summary\u003e\n\u003cp\u003ePossible causes include low dietary intake, alcohol, coeliac disease, malabsorption, pregnancy, increased cell turnover and medicines such as methotrexate, some antiepileptics and trimethoprim.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat does a high folate result mean?\u003c\/summary\u003e\n\u003cp\u003eA high serum folate result most often reflects recent food fortification or folic acid supplementation. It is not usually a toxicity diagnosis, but supplement use and vitamin B12 status should be reviewed.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eCan folic acid mask vitamin B12 deficiency?\u003c\/summary\u003e\n\u003cp\u003eYes. Folic acid can improve the anaemia caused by vitamin B12 deficiency while neurological injury continues. Vitamin B12 should be assessed before treating suspected folate deficiency.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eHow much folic acid is recommended before pregnancy?\u003c\/summary\u003e\n\u003cp\u003eUK guidance advises most people who may become pregnant to take 400 micrograms daily before conception and through the first 12 weeks of pregnancy. Higher dose folic acid is used only for defined higher risk situations under clinical advice.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat vitamin D level is considered deficient in the UK?\u003c\/summary\u003e\n\u003cp\u003eMany UK pathways classify a 25 hydroxyvitamin D result below 25 nmol\/L as deficient.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat vitamin D level is considered insufficient?\u003c\/summary\u003e\n\u003cp\u003eA level from 25 to 50 nmol\/L may be inadequate for some people. Symptoms, bone health, risk factors, supplements and local laboratory guidance affect management.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat vitamin D level is considered sufficient?\u003c\/summary\u003e\n\u003cp\u003eA result above 50 nmol\/L is considered sufficient for most adults in many UK pathways. Higher is not automatically better.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eCan vitamin D levels be too high?\u003c\/summary\u003e\n\u003cp\u003eYes. Very high vitamin D is most commonly caused by excessive supplementation and may lead to high calcium, causing thirst, frequent urination, nausea, constipation, weakness or confusion.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eCan low vitamin D cause tiredness or low mood?\u003c\/summary\u003e\n\u003cp\u003eLow vitamin D may coexist with tiredness, muscle weakness or bone pain, but these symptoms are non specific. A result should not be used to attribute all tiredness or mood symptoms to vitamin D.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhat tests may be needed after a low B12 or folate result?\u003c\/summary\u003e\n\u003cp\u003eA clinician may request a full blood count, blood film, active B12, methylmalonic acid, homocysteine, intrinsic factor antibodies, coeliac testing or other investigations based on symptoms and history.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eWhen are vitamin deficiency symptoms urgent?\u003c\/summary\u003e\n\u003cp\u003eSeek prompt medical assessment for new weakness, difficulty walking, rapidly worsening numbness, confusion, visual change, seizures, severe breathlessness, chest pain or symptoms during pregnancy.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cdetails\u003e\n\u003csummary\u003eAre the laboratories UKAS accredited and CQC registered?\u003c\/summary\u003e\n\u003cp\u003eSamples are processed through UKAS accredited laboratories within a CQC registered diagnostic pathway. Collection equipment is UKCA and CE marked and supported by an ISO 13485 quality management framework.\u003c\/p\u003e\n\u003c\/details\u003e\n\u003c\/section\u003e\n\u003csection class=\"vitamin_footer_note\"\u003e\n\u003ch3\u003eMedical guidance\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eThis panel measures selected vitamin concentrations. It does not diagnose the underlying cause of deficiency or replace a full blood count and clinical assessment.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSeek prompt medical assessment for new weakness, difficulty walking, rapidly worsening numbness, confusion, visual change, seizures, severe breathlessness, chest pain or concerning symptoms during pregnancy.\u003c\/p\u003e\n\u003cp\u003eDo not start high dose vitamin D or folic acid, or stop prescribed vitamin replacement, solely from a home result without appropriate advice.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003c\/article\u003e\n\n\u003c\/body\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":54409978708307,"sku":"476-essential-vitamins-t","price":99.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1088\/7918\/4211\/files\/Home_Vitamin_Deficiency_Test_UK_-_B12_Folate_Vitamin_D.png?v=1785173829"}],"url":"https:\/\/gracebelgravia.com\/collections\/frontpage.oembed","provider":"Grace Belgravia","version":"1.0","type":"link"}